Vismodegib

Category API

Details	Specifications
CAS Number	879085-55-9
Molecular Formula	C19H14Cl2N2O3S
Molecular Weight	421.3 g/mol.
Synonyms	2-Chloro-4-(methylsulfonyl)-N-[4-chloro-3-(2-pyridinyl) phenyl] benzamide
Chemical Name	2-Chloro-N-(4-chloro-3-(pyridin-2-yl)phenyl)-4-(methyl sulfonyl) benzamide
Common name	Vismodegib
Therapeutic use	Vismodegib is indicated for the treatment of adults with metastatic basal cell carcinoma, or with locally advanced basal cell carcinoma that has recurred following surgery or who are not candidates for surgery and who are not candidates for radiation
Background	Vismodegib is an orally active small molecule that inhibits the hedgehog signaling pathway by binding to and inhibiting the transmembrane protein smoothened homologue (SMO). It was discovered by high-throughput screening of a library of small-molecule compounds and subsequent optimization through medicinal chemistry.
Grade	In-house
Polymorph	Form-B
GTI	Risk assessment report available
Nitrosamines	Risk assessment report available
DMF Availability	-
Manufacturing batch size	--
Production capacity	--
Stability data	Available

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The information provided on this webpage is based on the best available knowledge at the time of publication; however, accuracy and completeness are not guaranteed. Product specifications may change without notice. It is the responsibility of the purchaser or user to verify suitability and compliance. This product is intended for research use only and is not approved for human consumption.

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