|
Details
|
Specifications
|
|---|---|
|
CAS Number
|
299-75-2
|
|
Molecular Formula
|
C6H14O8S2
|
|
Molecular Weight
|
278.29 g/mol.
|
|
Synonyms
|
Dihydroxy busulfan
|
|
Chemical Name
|
(2S,3S)-2,3-dihydroxy-4-(methane sulfonyl oxy) butyl methane sulfonate
|
|
Therapeutic use
|
Treosulfan showed hematopoietic stem cell depleting activity as well as immunosuppressive and antitumor activity in mouse models of leukemia. An increase in treosulfan exposure was associated with an increased incidence of infection-related death.
|
|
Status
|
Tech pack available
|
|
Background
|
Treosulfan is a prodrug alternative to busulfan for myeloablative conditioning prior to hematopoietic stem cell transplantation. It was approved by the EMA in June 2019 and by the FDA in January 2025 for use in combination with fludarabine.
|
|
Grade
|
In-house
|
|
Polymorph
|
Crystalline form
|
|
Storage Temperature
|
Controlled room temperature (20?C ? 25?C)
|
Please Note: We partner exclusively with pharmaceutical manufacturers, biotech companies, and international trading firms. Minimum order quantities apply*Â
Disclaimer:Â
The information provided on this webpage is based on the best available knowledge at the time of publication; however, accuracy and completeness are not guaranteed. Product specifications may change without notice. It is the responsibility of the purchaser or user to verify suitability and compliance. This product is intended for research use only and is not approved for human consumption.
Happy Customers
Projects Successfully Completed
Established
PhD Experts Driving R&D Excellence
Team Size
World-Class API Manufacturing Sites
Global Audits Successfully Completed
Comprehensive CDMO Service Offerings
Everything You Need to Know About Shilpa Pharma
Please Note: We partner exclusively with pharmaceutical manufacturers, biotech companies, and international trading firms. Minimum order quantities apply*
