Crizotinib

Category
Details
Specifications
CAS Number
877399-52-5
Molecular Formula
C21H22Cl22FN5O
Molecular Weight
450.34 g/mol.
Synonyms
Crizotinibum
Chemical Name
3-[(1R)-1-(2,6-dichloro-3-fluorophenyl) ethoxy]-5-(1-piperidin-4-ylpyrazol-4-yl) pyridin-2-amine
Therapeutic use
Crizotinib is a kinase inhibitor indicated for the treatment of patients with metastatic non-small cell lung cancer (NSCLC) whose tumors are anaplastic lymphoma kinase (ALK). Crizotinib is also indicated for the treatment of relapsed or refractory, systemic anaplastic large cell lymphoma (ALCL).
Status
Tech pack available
Background
Crizotinib was the first-in-class drug used to treat ALK-positive tumors. Crizotinib was approved by the FDA in 2011, and its use is accompanied by FDA-approved tests used to detect ALK and ROS1 rearrangements.
Grade
In-house
Polymorph
Form A
Storage Temperature
Controlled room temperature (20?C ? 25?C)

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The information provided on this webpage is based on the best available knowledge at the time of publication; however, accuracy and completeness are not guaranteed. Product specifications may change without notice. It is the responsibility of the purchaser or user to verify suitability and compliance. This product is intended for research use only and is not approved for human consumption.

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