Alectinib hydrochloride

Category
Details
Specifications
CAS Number
1256589-74-8
Molecular Formula
C30H34N4O2.HCl
Molecular Weight
519.08 g/mol.
Synonyms
Alectinib monohydrochloride
Chemical Name
[9-ethyl-6,6-dimethyl-8-[4-(morpholin-4-yl) piperidin-1-yl]-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile hydrochloride](
Therapeutic use
Used for the treatment of patients with anaplastic lymphoma kinase-positive, metastatic non-small cell lung cancer.
Status
Tech pack available
Background
Alectinib is a tyrosine kinase inhibitor that decreases tumor cell viability in multiple cell lines harboring ALK fusions, amplifications, or activating mutations. The major active metabolite of Alectinib, M4, showed similarity in vitro potency and activity. Received accelerated approval in the US (2015), followed by regular approval in 2017.
Grade
In-house
Polymorph
Form I
Storage Temperature
Controlled room temperature (20?C ? 25?C)

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The information provided on this webpage is based on the best available knowledge at the time of publication; however, accuracy and completeness are not guaranteed. Product specifications may change without notice. It is the responsibility of the purchaser or user to verify suitability and compliance. This product is intended for research use only and is not approved for human consumption.

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