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Details
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Specifications
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CAS Number
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877399-52-5
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Molecular Formula
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C21H22Cl22FN5O
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Molecular Weight
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450.34 g/mol.
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Synonyms
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Crizotinibum
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Chemical Name
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3-[(1R)-1-(2,6-dichloro-3-fluorophenyl) ethoxy]-5-(1-piperidin-4-ylpyrazol-4-yl) pyridin-2-amine
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Therapeutic use
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Crizotinib is a kinase inhibitor indicated for the treatment of patients with metastatic non-small cell lung cancer (NSCLC) whose tumors are anaplastic lymphoma kinase (ALK). Crizotinib is also indicated for the treatment of relapsed or refractory, systemic anaplastic large cell lymphoma (ALCL).
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Status
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Tech pack available
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Background
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Crizotinib was the first-in-class drug used to treat ALK-positive tumors. Crizotinib was approved by the FDA in 2011, and its use is accompanied by FDA-approved tests used to detect ALK and ROS1 rearrangements.
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Grade
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In-house
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Polymorph
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Form A
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Storage Temperature
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Controlled room temperature (20?C ? 25?C)
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Please Note: We partner exclusively with pharmaceutical manufacturers, biotech companies, and international trading firms. Minimum order quantities apply*Â
Disclaimer:Â
The information provided on this webpage is based on the best available knowledge at the time of publication; however, accuracy and completeness are not guaranteed. Product specifications may change without notice. It is the responsibility of the purchaser or user to verify suitability and compliance. This product is intended for research use only and is not approved for human consumption.
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Please Note: We partner exclusively with pharmaceutical manufacturers, biotech companies, and international trading firms. Minimum order quantities apply*