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Details
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Specifications
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CAS Number
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1269440-17-6
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Molecular Formula
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C22H27ClFN7O4S
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Molecular Weight
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540.01 g/mol.
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Synonyms
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(S)-methyl(1-((4-(3-(5-chloro-2-fluoro-3-(methylsulfonamido) phenyl)-1-isopropyl-1H-pyrazol-4-yl) pyrimidin-2-yl) amino) propan-2-yl) carbamate
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Chemical Name
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(S)-methyl (1-((4-(3-(5-chloro-2-fluoro-3-(methyl sulfonamido) phenyl)-1-isopropyl-1H-pyrazol-4-yl) pyrimidin-2-yl) amino) propan-2-yl) carbamate
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Therapeutic use
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Antimetabolite chemotherapy, Chemotherapy for pancreatic lung cancer, breast cancer and bladder cancer.
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Status
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Tech pack available
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Background
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Encorafenib (brand name Braftovi) is an oral, small-molecule kinase inhibitor designed to target and inhibit the activity of mutated BRAF proteins, specifically the V600E and V600K mutations. These mutations are key drivers of cancer growth, leading to constitutive activation of the MAPK signaling pathway, which is common in approximately 50% of melanomas.
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Grade
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In-house
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Polymorph
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Form A and Amorphous
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Storage Temperature
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Form A: Controlled room temperature (20?C ? 25?C) | Amorphous: Controlled temperature at 2?C ? 8?C.
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Please Note: We partner exclusively with pharmaceutical manufacturers, biotech companies, and international trading firms. Minimum order quantities apply*Â
Disclaimer:Â
The information provided on this webpage is based on the best available knowledge at the time of publication; however, accuracy and completeness are not guaranteed. Product specifications may change without notice. It is the responsibility of the purchaser or user to verify suitability and compliance. This product is intended for research use only and is not approved for human consumption.
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Please Note: We partner exclusively with pharmaceutical manufacturers, biotech companies, and international trading firms. Minimum order quantities apply*