Zanubrutinib

Category
Details
Specifications
CAS Number
1691249-45-2
Molecular Formula
C27H29N5O3
Molecular Weight
471.55 g/mol.
Synonyms
(S)-7-(1-acryloylpiperidin-4-yl)-2-(4-phenoxy phenyl)4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide.
Chemical Name
4-amino-1-[(2R,4R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl) oxolan-2-yl] pyrimidin-2-one; hydrochloride
Therapeutic use
Zanubrutinib is a kinase inhibitor used to treat mantle cell lymphoma, a type of B-cell non-Hodgkin lymphoma, in adults who previously received therapy.
Status
Tech pack available
Background
Zanubrutinib (marketed as Brukinsa) is a next-generation, oral, small-molecule inhibitor of Bruton?s tyrosine kinase (BTK) developed by BeiGene. It was designed to specifically target BTK to treat various B-cell malignancies.
Grade
In-house
Polymorph
Form A and Amorphous
Storage Temperature
Form A: Controlled room temperature (20?C ? 25?C) | Amorphous: Controlled temperature at 2?C ? 8?C.

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The information provided on this webpage is based on the best available knowledge at the time of publication; however, accuracy and completeness are not guaranteed. Product specifications may change without notice. It is the responsibility of the purchaser or user to verify suitability and compliance. This product is intended for research use only and is not approved for human consumption.

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Please Note: We partner exclusively with pharmaceutical manufacturers, biotech companies, and international trading firms. Minimum order quantities apply*