Topotecan Hydrochloride

Category API

Details	Specifications
CAS Number	119413-54-6
Molecular Formula	C23H24ClN3O5
Molecular Weight	457.9 g/mol.
Synonyms	9-[(Dimethylamino) methyl]-10-hydroxy-(20S)-Camptothecin hydrochloride
Chemical Name	(S)-10-((dimethylamino)methyl)-4-ethyl-4,9-dihydroxy-1H-pyrano [3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione hydrochloride
Common name	Topotecan hydrochloride
Therapeutic use	Ovarian cancer, Cervical cancer, Small cell lung carcinoma, lung cancer.
Background	Topotecan, sold under the brand name Hycamtin among others, is a chemotherapeutic agent medication that is a topoisomerase inhibitor. It is a synthetic, water-soluble analog of the natural chemical compound camptothecin. It is used in the form of its hydrochloride salt to treat ovarian cancer, lung cancer, and other cancer types.
Grade	In-house
Polymorph	Not existed
GTI	Risk assessment report available
Nitrosamines	Risk assessment report available
DMF Availability	--
Manufacturing batch size	0.4Kg
Production capacity	Annual capacity is 20 – 30 Kg
Stability data	--

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The information provided on this webpage is based on the best available knowledge at the time of publication; however, accuracy and completeness are not guaranteed. Product specifications may change without notice. It is the responsibility of the purchaser or user to verify suitability and compliance. This product is intended for research use only and is not approved for human consumption.

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