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Details
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Specifications
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CAS Number
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163451-81-8
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Molecular Formula
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C12H9F3N2O2
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Molecular Weight
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270.2 g/mol.
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Synonyms
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(Z)-2-cyano-N-(4-(trifluoromethyl) phenyl)-3-hydroxybut-2-enamide
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Chemical Name
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(Z)-2-cyano-N-(4-(trifluoromethyl) phenyl)-3-hydroxybut-2-enamide
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Common name
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Teriflunomide
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Therapeutic use
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Teriflunomide is a pyrimidine synthesis inhibitor with anti-inflammatory and immunomodulatory properties used to treat patients with the relapsing-remitting form of multiple sclerosis.
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Background
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Teriflunomide, marketed under the brand name [Aubagio](https://www.google.com/search?q=Aubagio&sca_esv=aebc27e24e1d4d26&ei=4c7HaZrLBu2PseMPxoTo8Ao&biw=1920&bih=945&oq=teriflunomide+background+brie&gs_lp=Egxnd3Mtd2l6LXNlcnAiHXRlcmlmbHVub21pZGUgYmFja2dyb3VuZCBicmllKgIIADIFECEYoAEyBRAhGKABSMcoUPcCWMofcAF4AZABAJgBlwGgAecEqgEDMC41uAEByAEA-AEBmAIGoAL2BMICChAAGLADGNYEGEfCAgUQIRifBZgDAIgGAZAGCJIHAzEuNaAHuxuyBwMwLjW4B_QEwgcDMS41yAcIgAgA&sclient=gws-wiz-serp&mstk=AUtExfD64eTfFGEFLfKDxUmAKp0FZirYgLqxu6l5o0cvHVVMwiTMSUCKdKl7i-oj0KmEySbpv_Qz7Wsz21wYytPmR_Z9xHK0iABt3DhT5-Gnsr9WnyYMXTEFTc7cb03F87HbxaU&csui=3&ved=2ahUKEwjP75Gn0cKTAxVrZGcHHcaaIsIQgK4QegQIARAB) (and available in generic forms), is a once-daily oral medication used to treat relapsing forms of multiple sclerosis (RMS), including relapsing-remitting MS (RRMS) and clinically isolated syndrome (CIS). It was approved by the FDA in 2012 and by the EMA in 2013.
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Grade
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EP
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Polymorph
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Not existed.
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GTI
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Risk assessment report available
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Nitrosamines
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Risk assessment report available
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DMF Availability
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USDMF# 32172, CEP 2023 - 313- Rev 00
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Manufacturing batch size
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2.0 Kg
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Production capacity
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Annual capacity is 200 - 300 Kg
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Stability data
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Available
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Please Note: We partner exclusively with pharmaceutical manufacturers, biotech companies, and international trading firms. Minimum order quantities apply*Â
Disclaimer:Â
The information provided on this webpage is based on the best available knowledge at the time of publication; however, accuracy and completeness are not guaranteed. Product specifications may change without notice. It is the responsibility of the purchaser or user to verify suitability and compliance. This product is intended for research use only and is not approved for human consumption.
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