Pemetrexed disodium

Category API

Details	Specifications
CAS Number	357166-30-4
Molecular Formula	C20H19N5Na2O6 • 2.5H2O
Molecular Weight	516.41 g/mol.
Synonyms	[Disodium N-(4-(2-amino-4-oxo-4,7-dihydro-1H-pyrrolo(2,3-d) pyrimidin-5-yl) ethyl) benzoyl)-L-glutamate hemi pentahydrate](https://www.ncbi.nlm.nih.gov/pcsubstance/?term=%22Disodium%20%20N-(4-(2-(2-amino-4-oxo-4%2C7-dihydro-1H-pyrrolo(2%2C3-d)pyrimidin-5-yl)ethyl)benzoyl)-L-glutamate%20%20hemipentahydrate%22%5bCompleteSynonym%5d%20AND%20135564527%5bStandardizedCID%5d)
Chemical Name	N-[4-[2-(2-amino-4,7-dihydro-4-oxo-1H-pyrrolo [2,3-d] pyrimidin-5-yl) ethyl] benzoyl]-L-glutamic acid disodium hemi pentahydrate
Common name	Pemetrexed disodium hemi Penta hydrate
Therapeutic use	Used to treat non-squamous non-small cell lung cancer
Background	Pemetrexed is a chemotherapy drug for use in combination with cisplatin for the treatment of patients with malignant pleural mesothelioma whose disease is either unresectable or who are otherwise not candidates for curative surgery. Its use in non-small cell lung cancer has also been investigated. Pemetrexed was first approved by the FDA on February 4, 2004.
Grade	EP & USP
Polymorph	Not existed.
GTI	Risk assessment report available
Nitrosamines	Risk assessment report available
DMF Availability	USDMF# 25102, R0 - CEP -2022 - 087 - Rev 00
Manufacturing batch size	20.0 Kg
Production capacity	Annual capacity 0.8 to 1.0 tonnes
Stability data	Available

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The information provided on this webpage is based on the best available knowledge at the time of publication; however, accuracy and completeness are not guaranteed. Product specifications may change without notice. It is the responsibility of the purchaser or user to verify suitability and compliance. This product is intended for research use only and is not approved for human consumption.

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