Cabozantinib (S)- Malate

Category
Details
Specifications
CAS Number
1140909-48-3
Molecular Formula
C28H24FN3O5.C4H6O5
Molecular Weight
635.6 g/mol.
Synonyms
Cabozantinib S malate
Chemical Name
N-(4-(6,7-dimethoxyquinolin-4-yloxy) phenyl)-N?-(4-fluorophenyl) cyclopropane-1,1-dicarboxamide, (2S)-hydroxybutanedioate
Therapeutic use
COMETRIQ is a kinase inhibitor indicated for the treatment of patients with progressive, metastatic medullary thyroid cancer (MTC).
Status
Tech pack available
Background
Cabozantinib (S)-malate used as a targeted therapy for several advanced cancers. It acts by inhibiting receptors involved in tumor growth, angiogenesis (new blood vessel formation), and metastasis, It was developed by Exelixis Inc. and is marketed under two main brand names for different indications: Cabometyx (tablets) and Cometriq (capsules)
Grade
In-house
Polymorph
--
Storage Temperature
Controlled room temperature (20?C ? 25?C)

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The information provided on this webpage is based on the best available knowledge at the time of publication; however, accuracy and completeness are not guaranteed. Product specifications may change without notice. It is the responsibility of the purchaser or user to verify suitability and compliance. This product is intended for research use only and is not approved for human consumption.

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