Orforglipron premix

Category Pipeline APIs

Details	Specifications
CAS Number	3008544-96-2
Molecular Formula	C48H48F2N10O5.1/2Ca.H2O (C6H9NO)n
Molecular Weight	921.02 g/mol.
Synonyms	-
Chemical Name	3-((1S, 2S)-1-(5-((S)-2, 2-dimethyltetrahydro-2H-pyran-4-yl)-2-((S)-3-(3-(4-fluoro-1-methyl-1H-indazol-5-yl)-2-oxo-2,3-dihydro-1H-imidazol-1-yl)-2-(4-fluoro-3,5-dimethylphenyl)-4-methyl-4,5,6,7-tetrahydro-2H-pyrazolo[4,3-c]pyridine-5-carbonyl)-1H-indol-1-yl)-2-methylcyclopropyl)-1,2,4-oxadiazol-5(4H)-onehemi calcium hydrate Crospovidone.
Therapeutic use	Type 2 diabetes and obesity
Status	Tech pack available
Background	Orforglipron hemicalcium hydrate is an investigational, once-daily oral, non-peptide GLP-1 receptor agonist designed to treat Type 2 diabetes and obesity. It acts as an agonist, promoting insulin secretion and reducing body weight (up to 5.4 kg in 4 weeks) and HbA1c, without requiring special food or water restrictions.
Grade	In-house
Polymorph	Amorphous
Storage Temperature	Controlled temperature at 2?C ? 8?C

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The information provided on this webpage is based on the best available knowledge at the time of publication; however, accuracy and completeness are not guaranteed. Product specifications may change without notice. It is the responsibility of the purchaser or user to verify suitability and compliance. This product is intended for research use only and is not approved for human consumption.

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