Ruxolitinib phosphate

Category API

Details	Specifications
CAS Number	1092939-17-7
Molecular Formula	C17H21N6O4P
Molecular Weight	404.36 g/mol.
Synonyms	Ruxolitinib monophosphate
Chemical Name	(R)-3-(4-(7H-pyrrolo[3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)-3-cyclopentylpropanenitrile phosphate
Common name	Ruxolitinib Phosphate
Therapeutic use	Various types of myelofibrosis, polycythemia vera
Background	Ruxolitinib phosphate is a kinase inhibitor indicated for treatment of patients with intermediate or high-risk myelofibrosis, including primary myelofibrosis, post-polycythemia vera myelofibrosis and post-essential thrombocythemia myelofibrosis.
Grade	EP
Polymorph	Not existed
GTI	Risk assessment report available
Nitrosamines	Risk assessment report available
DMF Availability	--
Manufacturing batch size	4.0 Kg
Production capacity	Annual capacity is 250 - 300Kg
Stability data	Available

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