Macitentan

Category API

Details	Specifications
CAS Number	441798-33-0
Molecular Formula	C19H20Br2N6O4S
Molecular Weight	588.27 g/mol.
Synonyms	N-[5-(4-Bromophenyl)-6-[2-[(5-bromo-2-pyrimidinyl) oxy] ethoxy] -4-pyrimidinyl]-N'-propyl sulfamide
Chemical Name	N-[5-(4-Bromophenyl)-6-[2-[(5-bromo-2-pyrimidinyl) oxy] ethoxy] -4-pyrimidinyl]-N'-propyl sulfamide
Common name	Macitentan
Therapeutic use	Macitentan is an endothelin receptor antagonist (ERA) approved for the treatment of pulmonary arterial hypertension (PAH). It relaxes blood vessels, decreasing pulmonary pressure and improving symptoms
Background	Macitentan is a dual endothelin receptor antagonist (ERA) approved in 2013 for treating Pulmonary Arterial Hypertension (PAH), notably reducing morbidity and mortality. It improves pulmonary artery pressure and exercise capacity by inhibiting ET receptors
Grade	In-house
Polymorph	Form-I
GTI	Risk assessment report available
Nitrosamines	Risk assessment report available
DMF Availability	-
Manufacturing batch size	--
Production capacity	--
Stability data	Available

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The information provided on this webpage is based on the best available knowledge at the time of publication; however, accuracy and completeness are not guaranteed. Product specifications may change without notice. It is the responsibility of the purchaser or user to verify suitability and compliance. This product is intended for research use only and is not approved for human consumption.

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