|
Details
|
Specifications
|
|---|---|
|
CAS Number
|
183133-96-2
|
|
Molecular Formula
|
C45H57NO14
|
|
Molecular Weight
|
835.93 g/mol.
|
|
Synonyms
|
[4-(Acetyloxy)-13alpha-(2R,3S)-3-[(tert-butoxy carbonyl) amino]-2-hydroxy-3-phenylpropanoyl} oxy)-1-hydroxy-7beta,10beta-dimethoxy-9-oxo-4alpha,5beta-5,20-epoxytax-11-en-2alpha-yl benzoate](https://www.ncbi.nlm.nih.gov/pcsubstance/?term=%224-(Acetyloxy)-13alpha-(%7B(2R%2C3S)-3-%5B(tert-butoxycarbonyl)amino%5D-2-hydroxy-3-phenylpropanoyl%7Doxy)-1-hydroxy-7beta%2C10beta-dimethoxy-9-oxo-4alpha%2C5beta-5%2C20-epoxytax-11-en-2alpha-yl%20benzoate%22%5bCompleteSynonym%5d%20AND%209854073%5bStandardizedCID%5d)
|
|
Chemical Name
|
1-hydroxy-7beta,10beta-dimethoxy-9-oxo-5beta,20-epoxytax-11-ene-2alpha,4,13alpha-triyl 4-acetate 2-benzoate 13-[(2R,3S)-3-{[(tertbutoxy)carbonyl] amino}-2-hydroxy-3-phenylpropanoate]
|
|
Common name
|
Cabazitaxel
|
|
Therapeutic use
|
Cabazitaxel injection is used along with prednisone to treat prostate cancer.
|
|
Background
|
Cabazitaxel is a novel taxane chemotherapy that is similar to, but distinct from, docetaxel. It is complex structure consisting of synthetically modified natural product with 2 additional methoxy groups added onto the docetaxel structure.
|
|
Grade
|
In house
|
|
Polymorph
|
Amorphous
|
|
GTI
|
Risk assessment report available
|
|
Nitrosamines
|
Risk assessment report available
|
|
DMF Availability
|
USDMF# 33087, ASMF # EU / ASMF / 00475
|
|
Manufacturing batch size
|
0.5 kg
|
|
Production capacity
|
Annual capacity is 12-15 kg
|
|
Stability data
|
Available
|
Please Note: We partner exclusively with pharmaceutical manufacturers, biotech companies, and international trading firms. Minimum order quantities apply*Â
Disclaimer:Â
The information provided on this webpage is based on the best available knowledge at the time of publication; however, accuracy and completeness are not guaranteed. Product specifications may change without notice. It is the responsibility of the purchaser or user to verify suitability and compliance. This product is intended for research use only and is not approved for human consumption.
Happy Customers
Projects Successfully Completed
Established
PhD Experts Driving R&D Excellence
Team Size
World-Class API Manufacturing Sites
Global Audits Successfully Completed
Comprehensive CDMO Service Offerings
Everything You Need to Know About Shilpa Pharma
Please Note: We partner exclusively with pharmaceutical manufacturers, biotech companies, and international trading firms. Minimum order quantities apply*
