Afatinib Dimaleate

Category API

Details	Specifications
CAS Number	850140-73-7
Molecular Formula	C32H33ClFN5O11
Molecular Weight	718.10 g/mol.
Synonyms	(S,E)-N-(4-((3-chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino) but-2-enamide Dimaleate
Chemical Name	2E)-N-{4-[(3-chloro-4-fluorophenyl) amino]-7-[(3S)-oxolan-3-yloxy] quinazolin-6-yl}-4-(dimethylamino) but-2-enimidic acid; bis((2Z)-but-2-enedioic acid)
Common name	Afatinib Dimaleate
Therapeutic use	Use as a treatment for non-small cell lung cancer
Background	Afatinib Dimaleate (brand name Gilotrif) was approved by the FDA in 2013. It inhibits ErbB1 (EGFR), ErbB2 (HER2), and ErbB4 receptors, blocking tumor growth, especially in tumors with common exon 19 deletions or L858R mutations.
Grade	In-house
Polymorph	Form-A
GTI	Risk assessment report available
Nitrosamines	Risk assessment report available
DMF Availability	-
Manufacturing batch size	-
Production capacity	-
Stability data	Available

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The information provided on this webpage is based on the best available knowledge at the time of publication; however, accuracy and completeness are not guaranteed. Product specifications may change without notice. It is the responsibility of the purchaser or user to verify suitability and compliance. This product is intended for research use only and is not approved for human consumption.

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