| Details | Specifications | |
|---|---|---|
|
CAS No. |
7682-20-4 |
|
|
Mol. Weight |
136.8 |
|
|
Appearance |
White to off white powder |
|
|
Synonyms
|
(S)-(+)-2-Aminobutanamide hydrochloride |
|
|
Storage |
Preserve in well closed container and store at controlled room temperature |
|
Disclaimer:Â
The information provided on this webpage is based on the best available knowledge at the time of publication; however, accuracy and completeness are not guaranteed. Product specifications may change without notice. It is the responsibility of the purchaser or user to verify suitability and compliance. This product is intended for research use only and is not approved for human consumption.
S-2-Aminobutanamide hydrochloride (CAS 7682-20-4), also known as (S)-(+)-2-aminobutanamide hydrochloride, is a chiral amino amide salt that serves as a key starting material (KSM) in the manufacture of antiepileptic active pharmaceutical ingredients. It is best recognised as Levetiracetam KSM-I, the foundational chiral building block from which the levetiracetam molecular framework is constructed, and it is equally relevant to the synthesis of the follow-on antiepileptic brivaracetam.
Supplied as a white to off-white powder with a molecular weight of 136.8 as published in the product specification, the compound provides the defined (S)-stereocentre that determines the pharmacological activity of the downstream API. Because the therapeutic activity of levetiracetam resides almost entirely in the S-configuration, the enantiomeric purity of this intermediate directly governs the quality, yield, and regulatory acceptability of the finished drug substance, making the choice of supplier a critical decision for API manufacturers.
As established API manufacturers in India, Shilpa Pharma Lifesciences supplies S-2-Aminobutanamide hydrochloride as a bulk API intermediate to pharmaceutical manufacturers worldwide. Backed by integrated CDMO services, Shilpa Pharma supports partners from development-scale evaluation through sustained commercial supply.
S-2-Aminobutanamide hydrochloride is supplied for use by pharmaceutical manufacturers as a key starting material in the multi-step synthesis of antiepileptic active pharmaceutical ingredients. In the levetiracetam route, the free amine liberated from the hydrochloride salt is condensed with a suitable four-carbon electrophile and cyclised to construct the 2-oxopyrrolidine acetamide core, with the pre-established (S)-stereocentre carried through to the final API without the need for a late-stage chiral resolution.
In a development and manufacturing context, the S-2-Aminobutanamide hydrochloride API intermediate supports process route development and optimisation, chiral method development and enantiomeric purity determination, impurity profiling and reference standard qualification, process validation batches, and scale-up to commercial campaigns. Its use as a pre-formed chiral synthon is a significant efficiency advantage, avoiding the yield losses inherent in resolving a racemate at a later stage of the sequence.
The material is provided exclusively to qualified pharmaceutical manufacturers, biotechnology companies, and international trading partners for development and manufacturing use under applicable regulatory frameworks.
As a pharmaceutical intermediate rather than a finished active, the relevant safety considerations for S-2-Aminobutanamide hydrochloride are occupational and chemical rather than clinical. The compound should be regarded as a potential irritant to the eyes, skin, and respiratory tract, and should be handled by trained personnel using appropriate engineering controls, local exhaust ventilation, and personal protective equipment including gloves, eye protection, and respiratory protection where dust generation is likely. Practices that minimise airborne dust during charging, sampling, and transfer operations are recommended.
The material should be preserved in a well closed container and stored at controlled room temperature, protected from moisture, to maintain quality and enantiomeric integrity over its shelf life. Complete handling, exposure control, first aid, and disposal guidance is provided in the product’s Safety Data Sheet (SDS), which should be reviewed before use.
This information is provided for scientific and technical reference to pharmaceutical professionals and does not constitute medical advice.
The cost of S-2-Aminobutanamide hydrochloride varies according to order volume, required specifications including enantiomeric purity limits, packaging, documentation, and delivery destination. As bulk intermediate pricing is project- and quantity-specific, Shilpa Pharma does not publish standard list pricing for this product.
For current S-2-Aminobutanamide hydrochloride pricing, bulk quantity cost estimates, and commercial supply terms, pharmaceutical buyers are invited to contact Shilpa Pharma directly. As a trusted S-2-Aminobutanamide hydrochloride supplier and exporter, Shilpa Pharma provides a tailored quotation based on the required quantity, specification, and documentation needs, along with competitive, cost-effective supply options that support long-term programme economics for both development-scale and commercial-scale requirements.
Shilpa Pharma Lifesciences is one of the most trusted S-2-Aminobutanamide hydrochloride manufacturers in India and a full-scale CDMO partner, supplying high-quality actives and intermediates to pharmaceutical companies across more than 80 countries. For this API intermediate, partners choose Shilpa Pharma for:
Partner with Shilpa Pharma, a trusted S-2-Aminobutanamide hydrochloride manufacturer and exporter, for a dependable, scalable, and cost-effective global source of this intermediate.
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Please Note: We partner exclusively with pharmaceutical manufacturers, biotech companies, and international trading firms. Minimum order quantities apply*
